It's time for Child's Play again. In case you don't know what it is, here's a blurb from the official site:
For the past three years, gamers and geeks around the world have raised nearly a million dollars in toys, games and cash for sick kids in Children's Hospitals across the globe through a grassroots charity called Child's Play.
Created by Penny Arcade, no "Administrative Fees" or other nonsense is collected; all gifts and donations go directly to the hospitals for distribution to sick kids.
Gabe, of Penny Arcade fame, put it in good perspective in his post, I'll quote a chunk here:
These hospitals obviously receive plenty of donations year round but what we learned is that the money they get for the most part is spent on things much more important than toys. Things like medicine and equipment are a bigger priority than say Crash Bandicoot.
These Kids need toys though. They need games to play and crafts to make in order to take their minds off their situations. Something as simple as a Game Boy can make the stay in one of these Hospitals much more bearable for a kid.
That pretty much sums it up. It's a good cause. Go do it.